Enter the Insulin Sensitivity, Glucose Effectiveness, Fasting Plasma Glucose, and Basal Insulin into the calculator to determine the Disposition Index.

Disposition Index Formula

The following formula is used to calculate the Disposition Index. 

DI = (I * G) / (F - B)

Variables:

  • DI is the Disposition Index
  • I is the Insulin Sensitivity (IS)
  • G is the Glucose Effectiveness (GE)
  • F is the Fasting Plasma Glucose (FPG)
  • B is the Basal Insulin (BI)

To calculate the Disposition Index, multiply the Insulin Sensitivity by the Glucose Effectiveness. Subtract the Basal Insulin from the Fasting Plasma Glucose. Divide the first result by the second result to get the Disposition Index.

What is a Disposition Index?

A Disposition Index is a clinical metric used in diabetes research to assess the body’s ability to regulate blood glucose levels. It is calculated by multiplying the body’s insulin sensitivity by its insulin response. A lower Disposition Index indicates a higher risk of developing type 2 diabetes, as it suggests that the body is not properly responding to insulin and/or is not producing enough insulin to maintain normal blood glucose levels.

How to Calculate Disposition Index?

The following steps outline how to calculate the Disposition Index (DI) using the formula: DI = (I * G) / (F – B).

  1. First, determine the value of Insulin Sensitivity (I) (IS).
  2. Next, determine the value of Glucose Effectiveness (G) (GE).
  3. Next, determine the value of Fasting Plasma Glucose (FPG) (F).
  4. Next, determine the value of Basal Insulin (BI) (B).
  5. Finally, calculate the Disposition Index (DI) using the formula DI = (I * G) / (F – B).
  6. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem:

Use the following variables as an example problem to test your knowledge:

Insulin Sensitivity (IS) (I) = 10

Glucose Effectiveness (GE) (G) = 5

Fasting Plasma Glucose (FPG) (F) = 100

Basal Insulin (BI) (B) = 20