Enter the Crown-Rump Length (CRL) into the calculator to estimate an approximate median nuchal translucency (NT) using a simplified (non-clinical) model. (NT is sometimes confused with the second-trimester nuchal fold measurement.)
Medical disclaimer: This calculator provides a simplified, non-clinical estimate and is not for diagnosis or medical decision-making. NT must be measured and interpreted by a qualified clinician using validated reference charts (percentiles/MoM), proper ultrasound technique, and the full clinical context.
Nuchal Translucency (NT) Formula
The following formula is a simplified linear model used by this calculator to approximate a median nuchal translucency (NT) in millimeters from the crown-rump length (CRL) in millimeters. It is intended only across the usual NT screening range of CRL ~45–84 mm (about 11–13+6 weeks).
NT \approx (CRL * 0.018) + 0.4
Variables:
- NT is the approximate median nuchal translucency (mm)
- CRL is the crown-rump length (mm)
To approximate NT, multiply the CRL by 0.018, then add 0.4. In clinical practice, NT interpretation is typically based on validated reference charts/percentiles (or MoM) for a given CRL/gestational age rather than a single linear equation.
What is Nuchal Translucency (NT)?
Nuchal translucency (NT) is the fluid-filled space at the back of a fetus’s neck measured on ultrasound during the first-trimester screening window (about 11–13+6 weeks, when CRL is roughly 45–84 mm). Increased NT can be associated with a higher risk of certain chromosomal conditions (such as trisomy 21/Down syndrome) and some structural or genetic conditions, but NT alone is not diagnostic and follow-up testing may be needed.
Note: NT is different from the second-trimester nuchal fold thickness measurement, which refers to soft-tissue thickness (not a fluid space) and is assessed later in pregnancy.
