Calculate solution strength, molarity, dilution, reconstitution, and serial dilution from mass, volume, concentration, and molecular weight.

Use final solution amounts. Dilution preserves the same solute; mass and molar concentration bases cannot be mixed. Clear concentrations before switching their basis. This calculation aid does not give medication-preparation instructions.


Related Calculators

Solution Strength Formula

The calculator supports percent strength, reconstitution, molarity, dilution, and serial dilution. The three percent conventions are defined below.

Weight/volume strength (% w/v):

% w / v = (mass of solute in g / final volume of solution in mL) ร— 100

Weight/weight percent (% w/w):

% w / w = (mass of solute / total mass of solution) ร— 100

Volume/volume percent (% v/v):

% v / v = (volume of solute / final volume of solution) ร— 100

Variables:

  • mass of solute: the dissolved substance, by mass
  • volume of solute: the dissolved liquid, by volume
  • final volume of solution: total volume after mixing, not just solvent added
  • total mass of solution: solute mass plus solvent mass
  • density: if a liquid solute is weighed, first calculate its volume separately as mass / density

Select the quantity to solve and enter the displayed known values. Percent modes use solute mass or volume and the final solution amount. Reconstitution uses mass = concentration ร— final volume; molarity additionally uses molar mass. Dilution uses C1V1 = C2V2 with compatible mass or molar concentrations. Serial dilution uses Cn = C0 / factorn with whole-number steps. Supported units are ยตg, mg, g, kg; ยตL, mL, L; molar concentrations; and the displayed mass concentrations. For a weighed liquid solute, divide mass by density separately before entering solute volume.

Reference Values

Common solution strengths used in labs, kitchens, and industry:

Solution Type Strength
Normal salinew/v0.9% (9 g/L NaCl)
D5W (dextrose IV)w/v5% (50 g/L)
Household bleachw/w~5โ€“6% NaOCl
Hydrogen peroxide (drugstore)w/w3%
Isopropyl alcohol (rubbing)v/v70% or 91%
Ethanol (denatured cleaner)v/v95%
Concentrated HClw/w~37%
Concentrated Hโ‚‚SOโ‚„w/w~98%

Approximate reference densities for separate mass-to-volume conversions. Use the actual reagent density at its measurement temperature for precise work; acid percentages below are w/w. Acid-stock density converts stock-solution mass to stock-solution volume, not pure-acid equivalent volume.

Liquid Approximate density (g/mL at 20ยฐC)
Water0.9982
Ethanol0.789
Methanol0.792
Isopropanol0.786
Acetone0.791
Glycerol1.261
Concentrated Hโ‚‚SOโ‚„ (98%)1.840
Concentrated HCl (37%)1.190

Worked Examples

Example 1 โ€” w/v. You need 250 mL of 0.9% saline. How much NaCl?

mass = (0.9 / 100) ร— 250 mL ร— 1 g/mL = 2.25 g NaCl. Dissolve in water and bring the final volume to 250 mL.

Example 2 โ€” v/v with density. You have 55.2 g of ethanol (density 0.789 g/mL) and want to dilute to 100 mL final volume. What is the resulting % v/v?

Solute volume = 55.2 / 0.789 = 69.96 mL. % v/v = 69.96 / 100 ร— 100 = 69.96%, essentially 70% v/v.

FAQ

Is % w/v the same as % w/w? No. w/v uses solution volume in the denominator (g per 100 mL), while w/w uses solution mass (g per 100 g). They only match when the solution density is exactly 1 g/mL.

Should I add solvent up to the final volume, or add the listed amount of solvent? Bring the solution up to the final volume. Mixing liquids often causes a small volume change, so adding “solute volume + solvent volume” will not give the right concentration.

Why does my w/w result come out over 100%? You probably entered solvent mass instead of total solution mass. The denominator is solute + solvent combined.

When do I need density for v/v? When the liquid solute is weighed, divide its mass by its density separately to obtain solute volume, then use the v/v mode.