Enter the area under the plasma concentration curve (mg ml-1 min) and the glomerular filtration rate (ml/min) into the Calculator. The calculator will evaluate the Dose Using the Calvert Equation.

## Dose Using the Calvert Equation Formula

D = AUC * (GFR + 25)

Variables:

- D is the Dose Using the Calvert Equation (mg)
- AUC is the area under the plasma concentration curve (mg ml-1 min)
- GFR is the glomerular filtration rate (ml/min)

To calculate Dose Using the Calvert Equation, add the glomerular filtration rate to 25, then multiply this result by the area under the plasma concentration curve.

## How to Calculate Dose Using the Calvert Equation?

The following steps outline how to calculate the Dose Using the Calvert Equation.

- First, determine the area under the plasma concentration curve (mg ml-1 min).
- Next, determine the glomerular filtration rate (ml/min).
- Next, gather the formula from above = D = AUC * (GFR + 25).
- Finally, calculate the Dose Using the Calvert Equation.
- After inserting the variables and calculating the result, check your answer with the calculator above.

**Example Problem : **

Use the following variables as an example problem to test your knowledge.

area under the plasma concentration curve (mg ml-1 min) = 15

glomerular filtration rate (ml/min) = 2.3