Enter the end-diastolic volume (mL) and the stroke volume (mL) into the Calculator. The calculator will evaluate the End-Systolic Volume. 

End-Systolic Volume Formula



  • ESV is the End-Systolic Volume (mL)
  • EDV is the end-diastolic volume (mL)
  • SV is the stroke volume (mL)

To calculate End-Systolic Volume, subtract the stroke volume from the end-diastolic volume.

How to Calculate End-Systolic Volume?

The following steps outline how to calculate the End-Systolic Volume.

  1. First, determine the end-diastolic volume (mL). 
  2. Next, determine the stroke volume (mL). 
  3. Next, gather the formula from above = ESV = EDV – SV.
  4. Finally, calculate the End-Systolic Volume.
  5. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem : 

Use the following variables as an example problem to test your knowledge.

end-diastolic volume (mL) = 140

stroke volume (mL) = 80


What is End-Diastolic Volume (EDV)?

End-Diastolic Volume (EDV) is the volume of blood in the ventricles at the end of diastole, right before the heart contracts. It is a critical factor in assessing cardiac function and health.

How does Stroke Volume (SV) affect cardiac output?

Stroke Volume (SV) is the amount of blood pumped by the left ventricle of the heart in one contraction. The cardiac output, which is the volume of blood the heart pumps per minute, is calculated by multiplying the stroke volume by the heart rate. Therefore, SV directly influences cardiac output.

Why is calculating End-Systolic Volume (ESV) important?

Calculating End-Systolic Volume (ESV) is important because it provides insights into the heart’s pumping efficiency and health. A higher ESV can indicate potential heart dysfunction, as it means more blood remains in the ventricle after contraction.

Can changes in EDV or SV indicate heart problems?

Yes, significant changes in either End-Diastolic Volume (EDV) or Stroke Volume (SV) can indicate heart problems. For instance, a decrease in EDV can signal reduced preload or ventricular filling, while a decrease in SV can indicate reduced cardiac output, possibly due to heart failure or valve issues.