Enter the initial and final values into the calculator to determine the fold change. This calculator helps to understand the increase or decrease in value, expressed as a ratio.

Fold Change Formula

The following formula is used to calculate the fold change:

FC = Final Value / Initial Value

Variables:

  • FC is the fold change
  • Final Value is the value at the end of the period
  • Initial Value is the value at the beginning of the period

To calculate the fold change, divide the final value by the initial value. The result is a ratio that represents the factor by which the initial value has increased or decreased to reach the final value.

What is Fold Change?

Fold change is a measure used in various fields such as finance, biology, and chemistry to describe how much a quantity changes between an original and a subsequent measurement. It is a ratio that compares the final value to the initial value, providing a simple way to express an increase or decrease. A fold change greater than 1 indicates an increase, while a fold change less than 1 indicates a decrease.

How to Calculate Fold Change?

The following steps outline how to calculate the fold change:


  1. First, determine the initial value of the quantity.
  2. Next, determine the final value of the quantity.
  3. Use the formula FC = Final Value / Initial Value.
  4. Finally, calculate the fold change (FC).
  5. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem:

Use the following variables as an example problem to test your knowledge.

Initial Value = 50

Final Value = 100