Enter the bilirubin level on day 7, bilirubin level on day 0, patient’s age, albumin level on day 0, and prothrombin time on day 0 into the calculator to determine the Lille Score.

Lille Score Formula

The following formula is used to calculate the Lille Score.

LS = 0.953 * (log (bilirubin day 7/bilirubin day 0)) – 0.101 * (age) + 0.147 * (albumin day 0) – 0.02 * (prothrombin time day 0) + 2.53

Variables:

  • LS is the Lille Score bilirubin
  • day 7 is the bilirubin level on day 7
  • bilirubin day 0 is the bilirubin level on day 0
  • age is the patient’s age
  • albumin day 0 is the albumin level on day 0
  • prothrombin time day 0 is the prothrombin time on day 0

To calculate the Lille Score, take the logarithm of the ratio of bilirubin level on day 7 to bilirubin level on day 0 and multiply it by 0.953. Subtract the product of the patient’s age and 0.101 from the result. Add the product of the albumin level on day 0 and 0.147 to the result. Subtract the product of the prothrombin time on day 0 and 0.02 from the result. Finally, add 2.53 to the result.

What is a Lille Score?

A Lille score is a clinical tool used to assess the response of patients with alcoholic hepatitis to corticosteroid treatment. It is calculated based on several factors including age, renal function, albumin level, bilirubin level, and prothrombin time. A high Lille score indicates a poor response to treatment and a higher risk of mortality, suggesting that alternative treatments may be necessary.

How to Calculate Lille Score?

The following steps outline how to calculate the Lille Score:

  1. First, determine the bilirubin level on day 7 (bilirubin day 7).
  2. Next, determine the bilirubin level on day 0 (bilirubin day 0).
  3. Next, determine the patient’s age (age).
  4. Next, determine the albumin level on day 0 (albumin day 0).
  5. Next, determine the prothrombin time on day 0 (prothrombin time day 0).
  6. Using the formula LS = 0.953 * (log (bilirubin day 7/bilirubin day 0)) – 0.101 * (age) + 0.147 * (albumin day 0) – 0.02 * (prothrombin time day 0) + 2.53, calculate the Lille Score (LS).
  7. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem:

Use the following variables as an example problem to test your knowledge:

bilirubin day 7 = 2.5

bilirubin day 0 = 1.8

age = 45

albumin day 0 = 3.2

prothrombin time day 0 = 14.5