Enter the ALT/AST ratio, BMI, gender, and diabetes mellitus status into the calculator to determine the Liver Steatosis Index.

## Liver Steatosis Formula

The following formula is used to calculate the Liver Steatosis Index (LSI).

LSI = 8 * (ALT/AST ratio) + BMI (+2, if female; +2, if diabetes mellitus) Variables:

• LSI is the Liver Steatosis Index ALT is the Alanine Aminotransferase level (U/L) AST is the Aspartate Aminotransferase level (U/L) BMI is the Body Mass Index (kg/m^2)Gender is represented by a binary variable (0 for male, 2 for female)Diabetes Mellitus is represented by a binary variable (0 for absence, 2 for presence)

To calculate the Liver Steatosis Index, multiply 8 by the ratio of ALT to AST, then add the BMI. If the patient is female, add 2 to the result. If the patient has diabetes mellitus, add another 2 to the result.

## What is a Liver Steatosis?

Liver steatosis, also known as fatty liver, is a condition characterized by the accumulation of excess fat in the liver. This can be caused by various factors such as excessive alcohol consumption, obesity, diabetes, or high cholesterol. If left untreated, it can lead to more serious liver diseases such as cirrhosis or liver cancer. It is often asymptomatic in the early stages, but can cause symptoms like fatigue, weight loss, and abdominal pain as it progresses.

## How to Calculate Liver Steatosis?

The following steps outline how to calculate the Liver Steatosis Index (LSI) using the given formula:

1. First, determine the ALT level (U/L).
2. Next, determine the AST level (U/L).
3. Next, determine the BMI (kg/m^2).
4. Next, determine the gender (0 for male, 2 for female).
5. Next, determine the presence of diabetes mellitus (0 for absence, 2 for presence).
6. Using the formula LSI = 8 * (ALT/AST ratio) + BMI (+2, if female; +2, if diabetes mellitus), calculate the Liver Steatosis Index.
7. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem:

Use the following variables as an example problem to test your knowledge:

ALT level (U/L) = 50

AST level (U/L) = 25

BMI (kg/m^2) = 28

Gender = 2 (female)

Diabetes Mellitus = 2 (presence)