Enter the Serum Iron and Total Iron Binding Capacity into the calculator to determine the Transferrin Saturation. This calculator can also evaluate any of the variables given the others are known.

Transferrin Saturation Formula

The following formula is used to calculate the Transferrin Saturation.

TS = (SI * 70.9) / TIBC


  • TS is the Transferrin Saturation (%) SI is the Serum Iron (µg/dL) TIBC is the Total Iron Binding Capacity (µg/dL)

To calculate the Transferrin Saturation, multiply the Serum Iron by 70.9, then divide the result by the Total Iron Binding Capacity. The result is the Transferrin Saturation in percentage.

What is a Transferrin Saturation?

Transferrin saturation is a medical diagnostic test that measures the percentage of transferrin, a protein that carries iron in the blood, that is saturated with iron. It is used to diagnose iron deficiency or iron overload disorders such as hemochromatosis. A low transferrin saturation indicates iron deficiency, while a high transferrin saturation indicates iron overload.

How to Calculate Transferrin Saturation?

The following steps outline how to calculate the Transferrin Saturation using the given formula:

  1. First, determine the value of Serum Iron (SI) in µg/dL.
  2. Next, determine the value of Total Iron Binding Capacity (TIBC) in µg/dL.
  3. Next, use the formula TS = (SI * 70.9) / TIBC to calculate the Transferrin Saturation.
  4. Finally, calculate the Transferrin Saturation using the obtained values.
  5. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem:

Use the following variables as an example problem to test your knowledge:

Serum Iron (SI) = 80 µg/dL

Total Iron Binding Capacity (TIBC) = 120 µg/dL