Enter the total cholesterol and the HDL-C (HDL cholesterol) into the calculator. The calculator will evaluate the atherogenic coefficient. 

Atherogenic Coefficient Calculator

Enter any 2 values to calculate the missing variable. Use the same unit system for both cholesterol inputs.

Medical note: This calculator is for educational use only and is not medical advice or a diagnosis. The atherogenic coefficient is only one lipid ratio and should be interpreted with other risk factors (for example blood pressure, diabetes, smoking, and LDL/non-HDL cholesterol) using guideline-based tools such as the ASCVD risk estimator; discuss results with a licensed clinician and refer to reputable guidance (e.g., CDC/NIH/AHA/ACC).

Related Calculators

Atherogenic Coefficient Formula

AC = (TC - HDL\text{-}C)/HDL\text{-}C

Variables:

  • AC is the atherogenic coefficient (unitless ratio)
  • TC is the total cholesterol
  • HDL-C is high-density lipoprotein cholesterol (HDL cholesterol)

To calculate the atherogenic coefficient, divide the difference between total cholesterol and HDL-C by HDL-C. Since TC − HDL-C is also called non-HDL cholesterol, you may also see this written as AC = non-HDL / HDL-C. Ensure both lab values use the same units (mg/dL or mmol/L).

How to Calculate Atherogenic Coefficient?

The following steps outline how to calculate the atherogenic coefficient.

  1. First, determine the total cholesterol. 
  2. Next, determine the HDL-C. 
  3. Next, gather the formula from above = AC = (TC-HDL-C)/HDL-C.
  4. Finally, calculate the atherogenic coefficient.
  5. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem : 

Use the following variables as an example problem to test your knowledge.

Total cholesterol = 200 mg/dL

HDL-C = 50 mg/dL

Atherogenic coefficient = (200 − 50) / 50 = 3.0

Frequently Asked Questions

What is the significance of calculating the atherogenic coefficient?

The atherogenic coefficient is one measure that can help describe the balance between total cholesterol and HDL cholesterol (HDL-C). It may be considered alongside other lipid measures and overall cardiovascular risk factors, rather than used as a standalone decision-making tool.

How can one improve their atherogenic coefficient?

Improving the atherogenic coefficient generally involves improving the overall lipid profile (for example, raising HDL-C and/or lowering non-HDL cholesterol). Common, clinician-recommended strategies include a heart-healthy eating pattern, regular physical activity, avoiding tobacco smoke, and maintaining a healthy weight.

Are there any limitations to using the atherogenic coefficient as a risk predictor?

While the atherogenic coefficient can provide helpful context, it is not the sole predictor of cardiovascular risk. Other factors, including genetic predispositions, lifestyle habits, blood pressure, diabetes status, and other lab measures, also play a crucial role. It’s important to consider a comprehensive approach when assessing cardiovascular risk.

Can the atherogenic coefficient be used for all age groups?

The atherogenic coefficient can be calculated for adults of all ages, but interpretation can vary depending on age, sex, and other individual factors. It’s advisable to consult with a healthcare provider for a thorough risk assessment.