Enter the concentration of globulin and albumin into the calculator to determine the albumin/globulin (A/G) ratio.

Albumin/Globulin (A/G) Ratio Calculator

Enter albumin and globulin from your lab report to calculate the A/G ratio. Tip: “Globulin” on many lab reports is calculated as Total Protein − Albumin. Use the value from your report (don’t guess).

Units: most U.S. lab reports use g/dL.

Medical note: For informational use only; not medical advice. Do not use this calculator to diagnose or treat any condition. Lab reference ranges and “globulin” calculations can vary by laboratory and must be interpreted with your other results, symptoms, and medical history. If you have concerning symptoms (such as jaundice, swelling, confusion, severe weakness/fatigue, chest pain, shortness of breath, or rapidly worsening illness), seek urgent medical care. Discuss abnormal results with a licensed clinician.

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Albumin/Globulin (A/G) Ratio Formula

The following formula is used to calculate the albumin/globulin (A/G) ratio for given concentrations of albumin and globulin.

R = A / G

Variables:

  • R is the albumin/globulin (A/G) ratio
  • A is the concentration of albumin
  • G is the concentration of globulin

To calculate the albumin/globulin (A/G) ratio, divide the concentration of albumin by the concentration of globulin.

What is an Albumin/Globulin (A/G) Ratio?

The albumin/globulin (A/G) ratio is a calculated value used to compare the amount of albumin to the total globulin fraction in blood (where globulin is generally estimated as total protein minus albumin). Globulins are a diverse group of proteins that include immunoglobulins and various transport and clotting-related proteins. Albumin is the most abundant plasma protein and helps maintain oncotic (osmotic) pressure and transport substances in the blood. The A/G ratio can help provide context when evaluating patterns seen with liver disease, kidney disease, inflammation, and certain immune or plasma cell disorders, but it is not diagnostic by itself.

How to Calculate Albumin/Globulin (A/G) Ratio?

The following steps outline how to calculate the Albumin/Globulin (A/G) Ratio.

  1. First, determine the concentration of albumin (A).
  2. Next, determine the concentration of globulin (G).
  3. Finally, calculate the A/G ratio using the formula R = A / G.
  4. After inserting the values and calculating the result, check your answer with the calculator above.

Example Problem : 

Use the following variables as an example problem to test your knowledge.

Concentration of globulin (G) = 2.5 g/dL

Concentration of albumin (A) = 3.5 g/dL