Enter the serum glutamic oxaloacetic transaminase (AST/SGOT) and the serum glutamic pyruvic transaminase (ALT/SGPT) into the Calculator. The calculator will evaluate the AST/ALT (SGOT/SGPT) Ratio. 

AST (SGOT) / ALT (SGPT) Ratio Calculator

Enter any 2 values to calculate the missing variable. Use the same unit for AST and ALT (commonly U/L or IU/L). The ratio is unitless.

Medical disclaimer: This calculator is for educational purposes only and does not provide medical advice or a diagnosis. AST/ALT results should be interpreted by a licensed clinician in the context of your symptoms, medical history, and other tests. If you have concerning symptoms (such as jaundice, confusion, or severe abdominal pain), seek urgent medical care.

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AST/ALT (SGOT/SGPT) Ratio Formula

SSR = AST/ALT

Variables:

  • SSR is the AST/ALT (SGOT/SGPT) ratio (unitless)
  • AST (SGOT) is the serum glutamic oxaloacetic transaminase
  • ALT (SGPT) is the serum glutamic pyruvic transaminase

To calculate the AST/ALT (SGOT/SGPT) Ratio, divide the serum glutamic oxaloacetic transaminase (AST/SGOT) by the serum glutamic pyruvic transaminase (ALT/SGPT).

How to Calculate AST/ALT (SGOT/SGPT) Ratio?

The following steps outline how to calculate the AST/ALT (SGOT/SGPT) Ratio.

  1. First, determine the serum glutamic oxaloacetic transaminase (AST/SGOT). 
  2. Next, determine the serum glutamic pyruvic transaminase (ALT/SGPT). 
  3. Next, gather the formula from above = SSR = AST/ALT.
  4. Finally, calculate the AST/ALT (SGOT/SGPT) Ratio.
  5. After inserting the variables and calculating the result, check your answer with the calculator above.

Example Problem : 

Use the following variables as an example problem to test your knowledge.

Serum glutamic oxaloacetic transaminase (AST/SGOT) = 9

Serum glutamic pyruvic transaminase (ALT/SGPT) = 14

FAQ

What does an abnormal SGOT/SGPT Ratio indicate?

An AST/ALT (SGOT/SGPT) ratio may help clinicians interpret patterns of liver enzyme elevation, but it cannot diagnose a specific condition on its own. Many factors (including medications, alcohol use, viral hepatitis, fatty liver disease, and muscle injury) can affect AST and ALT. Discuss your results with a healthcare professional.

Can medications affect the Sgot/Sgpt Ratio?

Yes, certain medications can affect liver enzymes and thus alter the Sgot/Sgpt Ratio. These include over-the-counter pain relievers, antibiotics, and statins. It’s important to inform your healthcare provider about all medications you are taking.

Is fasting required before testing for Sgot/Sgpt?

Fasting is not typically required before testing for serum glutamic oxaloacetic transaminase (SGOT) or serum glutamic pyruvic transaminase (SGPT), but it’s always best to follow the specific instructions provided by your healthcare provider or the testing facility.

How often should the Sgot/Sgpt Ratio be checked?

The frequency of testing depends on the individual’s health status, underlying conditions, and risk factors for liver disease. Your healthcare provider can provide personalized advice on how often you should have your Sgot/Sgpt Ratio checked.